Frequent occurrence of cytogenetic abnormalities in sporadic nonmedullary thyroid carcinoma
نویسندگان
چکیده
منابع مشابه
Familial nonmedullary thyroid carcinoma.
BACKGROUND Nonmedullary thyroid carcinomas (NMTCs) originate from the thyroid epithelial cells and, until recently, were thought to arise sporadically without an inherited genetic predisposition. However, evidence of a familial predisposition to NMTC is accumulating. METHODS This review addresses the strengths, weaknesses, and clinical implications of the observations indicating an inherited ...
متن کاملTreatment of sporadic nonmedullary thyroid carcinomas in pediatric age.
Nonmedullary thyroid carcinomas are rare malignancies in pediatric ages. The vast majority of them are papillary carcinomas with an overall survival of approximately 100%. Their outcome is independent of strong prognostic factors of adults, such as papillary carcinoma histological subtype, invasion into soft tissue of the neck, presence and site of distant metastases, relapse and type of surger...
متن کاملClinicopathologic Features of Familial Nonmedullary Thyroid Carcinoma
BACKGROUND Familial nonmedullary thyroid carcinoma (FNMTC) is a variant of nonmedullary thyroid carcinoma(NMTC) with particular clinicopathologic features. In recent years, a number of studies have shown that FNMTC is more invasive than sporadic NMTC(SNMTC). The purpose of this study was to explore the differences in clinicopathologic features of FNMTC between different types of families and to...
متن کاملFamilial Nonmedullary Thyroid Cancer
FAMILIAL NONMEDULLARY THYROID CANCER (Abstract): Follicular cell-derived thyroid cancer which represents 90-95% of all thyroid malignancies may occur in at least 5% of cases as familial disease. Familial nonmedullary thyroid cancer (FNMTC) is defined as the existence of two or more first degree relatives affected within a family. FNMTC may occur in two situations: pure FNMTC in which FNMTC is t...
متن کاملFamilial Nonmedullary Thyroid Carcinoma: A Retrospective Analysis of 117 Families
Background The first and most important step in characterizing familial nonmedullary thyroid carcinoma (NMTC) is to distinguish the true familial patients, which is the prerequisite for all accurate analyses. This study aimed to investigate whether patients from families with ≥3 first-degree relatives affected with NMTC have different characteristics than patients from families with only two af...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cancer
سال: 1990
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(19900915)66:6<1213::aid-cncr2820660622>3.0.co;2-9